B Cell Engineering Services by Editing at Safe Harbor Locus

Selecting a suitable genomic site for the integration of transgene is a key step in B cell engineering. Genomic safe harbor (GSH) loci are well-known safe integration sites without negative effects on the host cell. Therefore, transgenes usually are designed to insert into GSH sites, further improving the safety and efficiency of gene therapy. Several GSH sites have been identified including AAVS1, CCR5, and Rosa26. Learn more: B Cell Engineering Services by Editing at Safe Harbor Locus

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