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Conventional iPSC factor

Conventional iPSC factor reprogramming is based on integrating vectors with the problems of cell death, residual expression, and re-activation of reprogramming factors, immunogenicity, uncontrolled silencing of transgenes, and insertional mutagenesis. Methods of factor reprogramming fall into two broad categories: chemical and transgene reprogramming. It has been reported that many small molecules promote reprogramming when used with the classical reprogramming factors.

Posted on : Wed, Feb 19, 2025 8:30 AM

Posted By : cailynn johnson