Why can Malegra 50 Mg cause headaches?

Malegra 50 mg contains sildenafil, the same active ingredient used in many erectile dysfunction medicines. Headaches are one of the most common side effects because sildenafil widens blood vessels (vasodilation) throughout the body — not only in the penis. When blood vessels in the brain expand, Malegra 50 Mg and blood flow changes can trigger a headache. (nhs.uk) Sildenafil works by blocking an enzyme called PDE-5, which increases nitric oxide activity and relaxes smooth muscles in blood vessels. This effect improves erections but can also affect circulation in the head and face, leading to headache, flushing, and dizziness. (mayoclinic.org) Headaches are usually mild to moderate and often improve as the medicine wears off. Dehydration, alcohol use, taking a higher dose than needed, or combining the tablet with heavy meals can make symptoms worse. Some people are simply more sensitive to sildenafil’s blood-vessel effects.  

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